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Layers Of The Bladder

Bladder Cancer, Causes, Signs and Symptoms, Diagnosis and Treatment.

Your bladder is made up of layers:

  • The first layer is the lining on the inside of your bladder. It is called the transitional epithelium or urothelium.
  • The second layer is a thin layer of connective tissue called the lamina propria.
  • The third layer is muscle tissue called the muscularis propria.
  • The fourth layer is fatty connective tissue. It separates the bladder from other body organs, such as the prostate and kidneys.

Doctors describe your bladder cancer based on how far it has spread through these layers. You can have:

  • non muscle invasive bladder cancer – the cancer is only in the lining or the connective tissue beneath the bladder lining
  • invasive bladder cancer – the cancer has grown into a deeper layer of the bladder, or beyond

Most bladder cancers start in the inner lining of the bladder. This lining has 2 names:

  • the transitional epithelium

The bladder lining is made up of cells called transitional cells. Cancers that start in these cells are called transitional cell bladder cancers. Doctors also call them urothelial cancers.

Transitional cell bladder cancers are the most common type of bladder cancer. There are rare types of bladder cancer that start in different types of cell in the bladder.

Pain Where Bladder Is Located Other Possible Causes

Some of the other reasons you may have pain where the bladder is located are a damaged urethra and a weak and neurogenic bladder.

If pain where bladder is located is an issue for you, seek help immediately or start using the associated treatments. Dont allow the problem to get any worse.

Medical Disclaimer

The information contained in this post is for general information purposes only. The information is provided by PainBalance.org and while we endeavor to keep the information up to date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability or availability with respect to the website or the information, products, services, or related graphics contained on the post for any purpose.

As noted, you should always consult with your doctor for medical advice to be sure of the issue you are experiencing.

Pain Where Bladder Is Located

If you have pain where bladder is located, it could come from various medical issues. You will learn some of the most common causes of bladder pain.

The information is helpful, but we always recommend seeing a doctor first if you can, Rather than seeking to do your self-help program.

We understand that not everyone may have access to medical care, free or otherwise. This information will have value for such persons.

Firstly, it is essential to follow the guidelines and not cut corners. Your health matters you shouldnt take unnecessary chances.

The first rule is to compare your symptoms with the signs of each disease we share. Eliminate any that dont apply.

Once you have finished that process, compare the remaining results for the treatments available.

The remedies that match would be the starting point of your treatment to a better you. This method will never fail if you follow it correctly.

First and foremost, you should still try to get medical advice and attention.

Here are the conditions that cause pain where bladder is located for those unable to do so.


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Save your digestion. Watch this NOW.

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How Will I Feel After A Hysterectomy


After a hysterectomy, your periods will stop. Occasionally, you may feel bloated and have symptoms similar to when you were menstruating. It is normal to have light vaginal bleeding or a dark brown discharge for about four to six weeks after surgery.

You may feel discomfort at the incision site for about four weeks, and any redness, bruising or swelling will disappear in four to six weeks. Feeling burning or itching around the incision is normal. You may also experience a numb feeling around the incision and down your leg. This is normal and, if present, usually lasts about two months. Its normal to have scarring, both internally and externally. Laparoscopic surgeries will cause smaller, less visible scars as opposed to abdominal hysterectomy.

If the ovaries remain, you should not experience hormone-related effects. If the ovaries were removed with the uterus before menopause, you may experience the symptoms that often occur with menopause, such as hot flashes. Your healthcare provider may prescribe hormone replacement therapy to relieve menopausal symptoms.

People who undergo a subtotal hysterectomy may continue to have a light period for a year after the procedure. This happens because small amounts of the endometrial lining can remain in the cervix, causing light periods.


Emotional reactions to a hysterectomy vary and can depend on how well you were prepared for the surgery, the reason for having it and whether the problem has been treated.

How Does Urination Occur


To urinate, your brain signals the sphincters to relax. Then it signals the muscular bladder wall to tighten, squeezing urine through the urethra and out of your bladder.

How often you need to urinate depends on how quickly your kidneys produce the urine that fills the bladder and how much urine your bladder can comfortably hold. The muscles of your bladder wall remain relaxed while the bladder fills with urine, and the sphincter muscles remain contracted to keep urine in the bladder. As your bladder fills up, signals sent to your brain tell you to find a toilet soon.

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Bladder Anatomy Location Parts And Pictures

Posted by Dr. Chris

The urinary bladder is a hollow muscular organ located in the lesser pelvis when empty. It serves as a reservoir for urine and can stretch considerably to store close to a maximum of 500 milliliters of urine. The average full bladder that is not overly distended contains about 350 milliliters of urine. It receives urine produced in the kidneys via the ureters and passes it out into the external environment through the urethra.

Bladder Conditions And Symptoms

The first and most important point to remember is that everyone with a bladder problem can be helped and many can be completely cured.

If you have been diagnosed with incontinence problems, you can use the bladder menu to find out more information about your specific bladder condition or problem. If you have not been diagnosed by a health professional, the following questions about your symptoms should help you find the information you are looking for.

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The Upper And Lower Urinary Tracts

The urinary system has two parts: the upper urinary tract and the lower urinary tract. Together, the two kidneys and two ureters make up the upper urinary tract. The lower urinary tract contains the bladder and the urethra. Men and women have the same upper urinary tract, but their lower urinary tracts are different.

Blood Supply And Lymphatics

Gallbladder Symptoms and What To DO

The superior and inferior vesicle arteries provide the blood supply to the bladder. These are indirect branches of the internal iliac arteries. The bladder also receives some of its blood supply from the obturator artery and the inferior gluteal artery. In some cases, the inferior vesicle artery may be a branch of the internal pudendal artery.

Blood is drained from the bladder via the vesical venous plexus that empties into the internal iliac vein. Lymphatics are drained via various lymph nodes associated with the veins in the area, with most of the drainage occurring via the external iliac lymph nodes.

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When Should I Call My Doctor If I Think I Might Have A Problem With My Urinary Tract

If youre having trouble or pain when urinating, you should visit your doctor. It may be a sign of an infection or another condition. Call your doctor if you have:

  • Blood in your urine.
  • Burning sensation, pain or difficulty urinating.
  • Pain in your pelvic area, lower back, genital area, or flank .
  • Trouble holding your urine or problems with leaking urine.

A note from Cleveland Clinic

Your urinary system plays a critical role in keeping you alive. It filters your blood and removes waste and excess water through urine. Your urinary system includes your kidneys, ureters, bladder and urethra. Conditions like urinary tract infections, sexually transmitted diseases, kidney diseases, and urinary tract obstruction can affect the health of your urinary system. If you have one of these conditions, talk to your healthcare provider about steps you can take to ensure your health.

Last reviewed by a Cleveland Clinic medical professional on 12/05/2019.


Differences Between Male And Female Urinary Tracts

Men and women have lower urinary tracts that carry out the same job of storing and releasing urine from the body.2,3 However, parts of the male and female lower urinary tracts are structured differently. The bladder is the same, but the urethra is not. The urethra is a thin tube that carries urine from the bladder out of the body during urination.

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Pain Where Bladder Is Located More Causes

Bladder pain can be due to some severe conditions that could become deadly. Living with bladder disease is life-changing as you require devices to help you cope.

Having a desire to urinate and being unable to do so is very irritating and uncomfortable. It is vital to seek help before such conditions worsen and become permanent.

There are some other causes of pain where bladder is located for you to see, so keep reading.

Blood And Lymph Supply

Female Pelvic Anatomy

The bladder receives blood by the vesical arteries and drained into a network of vesical veins. The superior vesical artery supplies blood to the upper part of the bladder. The lower part of the bladder is supplied by the inferior vesical artery, both of which are branches of the internal iliac arteries. In females, the uterine and vaginal arteries provide additional blood supply. Venous drainage begins in a network of small vessels on the lower lateral surfaces of the bladder, which coalesce and travel with the lateral ligaments of the bladder into the internal iliac veins.

The lymph drained from the bladder begins in a series of networks throughout the mucosal, muscular and serosal layers. These then form three sets of vessels: one set near the trigone draining the bottom of the bladder one set draining the top of the bladder and another set draining the outer undersurface of the bladder. The majority of these vessels drain into the external iliac lymph nodes.

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What Causes Bladder Stones

Bladder stones usually form when you can’t completely empty your bladder of urine.

A common reason for this in men is having an enlarged prostate gland that blocks the flow of urine.

If urine sits in the bladder for a long time, chemicals in the urine form crystals, which harden into bladder stones.

Read more about the causes of bladder stones and who’s at risk.

What Are Some Of The Causes Of Chronic Kidney Disease

Chronic kidney disease is defined as having some type of kidney abnormality, or marker, such as protein in the urine and having decreased kidney function for three months or longer.

There are many causes of chronic kidney disease. The kidneys may be affected by diseases such as diabetes and high blood pressure. Some kidney conditions are inherited .

Others are congenital that is, individuals may be born with an abnormality that can affect their kidneys. The following are some of the most common types and causes of kidney damage.

Diabetes is a disease in which your body does not make enough insulin or cannot use normal amounts of insulin properly. This results in a high blood sugar level, which can cause problems in many parts of your body. Diabetes is the leading cause of kidney disease.

High blood pressure is another common cause of kidney disease and other complications such as heart attacks and strokes. High blood pressure occurs when the force of blood against your artery walls increases. When high blood pressure is controlled, the risk of complications such as chronic kidney disease is decreased.

Glomerulonephritis is a disease that causes inflammation of the kidneys tiny filtering units called the glomeruli. Glomerulonephritis may happen suddenly, for example, after a strep throat, and the individual may get well again.However, the disease may develop slowly over several years and it may cause progressive loss of kidney function.

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Kidney And Urinary System Parts And Their Functions

  • Two kidneys. This pair of purplish-brown organs is located below the ribs toward the middle of the back. Their function is to:

  • Remove waste products and drugs from the body

  • Balance the body’s fluids

  • Release hormones to regulate blood pressure

  • Control production of red blood cells

The kidneys remove urea from the blood through tiny filtering units called nephrons. Each nephron consists of a ball formed of small blood capillaries, called a glomerulus, and a small tube called a renal tubule. Urea, together with water and other waste substances, forms the urine as it passes through the nephrons and down the renal tubules of the kidney.

  • Two sphincter muscles. These circular muscles help keep urine from leaking by closing tightly like a rubber band around the opening of the bladder.

  • Nerves in the bladder. The nerves alert a person when it is time to urinate, or empty the bladder.

  • Urethra. This tube allows urine to pass outside the body. The brain signals the bladder muscles to tighten, which squeezes urine out of the bladder. At the same time, the brain signals the sphincter muscles to relax to let urine exit the bladder through the urethra. When all the signals occur in the correct order, normal urination occurs.

  • How Does The Bladder Store Urine

    Pharmacology – BPH, Bladder control, Urinary meds for nursing RN PN NCLEX

    When it is empty, an adults bladder is about the size and shape of a pear. The bladder is very flexible, like a balloon, which means it can expand and get bigger when it is full of urine. In most adults, the bladder can expand to hold about one pint of urine before they feel the urge to urinate. When the bladder is empty after urinating, it shrinks back down to its empty size.

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    The Bladder And Kidneys

    The kidneys filter waste products out of the blood, which are mixed with water to create urine. Urine flows from the kidneys to the bladder, where it’s stored.

    When the bladder is full and you’re ready to pee, urine passes out of your body through a tube called the urethra.

    Page last reviewed: 22 March 2022 Next review due: 22 March 2025

    Understanding Bladder Infection Signs

    It is crucial to always listen to the bladder infection signs that your body is giving you. Leaving an infection untreated is dangerous and could be deadly.

    If you feel that you could be experiencing an infection, the best course of action is to contact a healthcare professional as soon as symptoms arise.

    For more information on how you can get the healthcare, you need .

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    Kidney Pain Location And Sensation

    Most people tend to associate pain in the area between the ribs and hips as either digestive problems or muscular back pain. However, kidney pain isnt always felt in the same place as the kidneys location.

    Dr. Charles Patrick Davis on MedicineNet explains that renal or flank pain can be felt anywhere between the lowest rib and the buttocks. The pain may also radiate to the groin or abdominal area. Depending on the underlying cause of the kidney pain, you may feel the pain in just the left or right side of your back. However, sometimes kidney pain affects both sides of the back.3

    Layers Of The Bladder Wall

    Anatomy Of Female Urinary Bladder Stock Illustration

    The wall of the bladder wall has three principal tissue layers or coats:

    Lies beneath the epithelial layer single layer of cells separating the epithelial layer from the lamina propria a sheet of extracellular material serving as a filtration barrier and supporting structure for the mucosal layer

    Submucous coat Areolar connective tissue interlaced with the muscular coat. This layer contains blood vessels, nerves, and in some regions, glands. A tumor, which has spread to this layer, can metastasize to the rest of the body via the lymphatics and blood vessels.

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    Expert Review And References

    • Al-Ahmadie H, Lin O, Reuter VE. Pathology and cytology of tumors of the urinary tract. Scardino PT, Lineham WM, Zelefsky MJ, Vogelzang NJ . Comprehensive Textbook of Genitourinary Oncology. 4th ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins 2011: 16:295-316.
    • American Cancer Society. About Bladder Cancer. 2016: .
    • American Society of Clinical Oncology. Bladder Cancer. 2017: .
    • Martini FH, Timmons MJ, Tallitsch RB. Human Anatomy. 7th ed. San Francisco: Pearson Benjamin Cummings 2012.
    • National Cancer Institute. Bladder Cancer Treatment Health Professional Version. 2018: .
    • Surveillance Epidemiology and End Results , National Cancer Institute. SEER Training Modules: Anatomy of the Bladder. Bethesda, MD: National Cancer Institute .

    Promoting Good Bladder Health

    Sometimes, there is no choice but to hold urine, but it may not be good for the bladder. Holding your urine for a short period of time, usually up to one hour, is typically okay, Ramin said. However, protracted and repeated holding of urine may cause over-expansion of bladder capacity, transmission of excess pressure into the kidneys, and the inability to completely empty the bladder. These problems in turn may lead to UTI , cystitis and deterioration of kidney function.

    Drinking plenty of water throughout the day can also help prevent bladder stones by preventing the concentration of minerals that cause the stones. The Mayo Clinic suggests asking a medical profession about how much water the body needs according to age, size and activity level.

    Editors Note: If youd like more information on this topic, we recommend the following book:

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