Monday, January 30, 2023

Side Effects Of Bladder Cancer

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Side Effects Of Turbt

Managing side effects in treatment of bladder cancer

The side effects of TURBT are generally mild and dont usually last long. After TURBT there might be bleeding and pain when the patient urinates. They may be go home from the hospital the very same day or the next day. Normal activities may resume within a week or two.

Bladder cancer often recurs in other parts of the bladder despite a TURBT. Another TURBT can help treat this. However, if repetition of the procedure occurs multiple times, the bladder is susceptible to scars and may lose its ability to retain urine. This may cause side effects like incontinence or frequent urges to use the washroom.

For patient with recurrent and non-invasive low-grade tumors which are slow-growing tumors and tumors that keep coming back, the surgeon may advice fulguration to burn small tumors that a cystoscopy reveals instead of removing them. A local anesthesia precedes this fulguration. This is safe but it may cause mild discomfort.

Risk Factors For Bladder Cancer

There are some things that can make you more likely to develop bladder cancer. These are called risk factors and they include:

  • smoking chemicals in cigarettes can cause bladder cancer, so if you smoke, your risk is up to three times that of a non-smoker
  • age most people with bladder cancer are over 60 years of age
  • family history a first degree relative with bladder cancer increases risk up to nearly 2 times higher than the general population
  • chemicals being in contact with certain chemicals for a long period of time, like aromatic amines, benzene products and aniline dyes, which have been linked to bladder cancer
  • frequent infections of the bladder over a long period of time
  • some types of radiation therapy around the pelvis, and the chemotherapy drug cyclophosphamide.

Having these risk factors doesnt mean you will develop bladder cancer. Often there is no clear reason for getting bladder cancer. If you are worried about your risk factors, ask your doctor for advice.

When To See A Doctor

There are a few side effects that can be especially dangerous, so make sure to talk to your doctor if you notice that you:

  • Have a severe skin rash
  • Are wheezing or having difficulty breathing
  • Are finding swallowing to be difficult
  • Have a high fever that isnt lowered with Tylenol or other over-the-counter fever reducers

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What Are The Symptoms Of Bladder Cancer

Many people with bladder cancer can have blood in their urine but no pain while urinating. There are a number of symptoms that might indicate bladder cancer like fatigue, weight loss, and bone tenderness, and these can indicate more advanced disease. You should pay particular attention to the following symptoms:

Your doctor can rate bladder cancer with a staging system that goes from stages 0 to 4 to identify how far the cancer has spread. The stages of bladder cancer mean the following:

  • Stage 0 bladder cancer hasnt spread past the lining of the bladder.
  • Stage 1 bladder cancer has spread past the lining of the bladder, but it hasnt reached the layer of muscle in the bladder.
  • Stage 2 bladder cancer has spread to the layer of muscle in the bladder.
  • Stage 3 bladder cancer has spread into the tissues that surround the bladder.
  • Stage 4 bladder cancer has spread past the bladder to the neighboring areas of the body.

Your doctor will work with you to decide what treatment to provide based on the type and stage of your bladder cancer, your symptoms, and your overall health.

Risk Factor: Chemical Exposure

Side Effects of BCG for Bladder Cancer

Research suggests that certain jobs may increase your risk for bladder cancer. Metal workers, mechanics, and hairdressers are among those who may be exposed to cancer-causing chemicals. If you work with dyes, or in the making of rubber, textiles, leather, or paints, be sure to follow safety procedures to reduce contact with dangerous chemicals. Smoking further increases risk from chemical exposure.

Anyone can get bladder cancer, but these factors put you at greater risk:

  • Gender: Men are three times more likely to get bladder cancer.
  • Age: Nine out of 10 cases occur over age 55.
  • Race: Whites have twice the risk of African-Americans.

Other factors at play include a family history of bladder cancer, previous cancer treatment, certain birth defects of the bladder, and chronic bladder irritation.

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Bladder Cancer Symptoms: Blood In Urine

One sign of bladder cancer is blood in the urine, also known as hematuria. Blood in the urine does not always mean bladder cancer. Hematuria is most often caused by other conditions like trauma, infection, blood disorders, kidney problems, exercise, or certain medications. Blood in the urine may be seen by the naked eye or only detected on urine testing . The urine may be discolored and appear brownish or darker than usual or, rarely, bright red in color.

Going Home For The First Time After Surgery

Due to the post-op complications, I was bouncing between the hospital and a rehab facility for 2 months before I was discharged home. I took some time to adjust to being home with a urostomy. I wanted to enjoy my birthday 5 days after returning home and Thanksgiving a few days after that. The week after Thanksgiving, I saw my oncologist, got my port, and started chemo.

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Who Can Have This Treatment

BCG is appropriate for noninvasive and minimally invasive bladder cancers. It usually follows a procedure called transurethral resection of bladder tumor . Its intended to help prevent recurrence.

This treatment only affects cells inside the bladder. Its not useful for later stage bladder cancer that has spread into or beyond the bladder lining, or to other tissues and organs.

Changes In Bladder Habits Or Symptoms Of Irritation

Mental Health Side Effects and Treatments for Sexual Dysfunction after Bladder Cancer Treatment

Bladder cancer can sometimes cause changes in urination, such as:

  • Having to urinate more often than usual
  • Pain or burning during urination
  • Feeling as if you need to go right away, even when your bladder isn’t full
  • Having trouble urinating or having a weak urine stream
  • Having to get up to urinate many times during the night

These symptoms are more likely to be caused by a urinary tract infection , bladder stones, an overactive bladder, or an enlarged prostate . Still, its important to have them checked by a doctor so that the cause can be found and treated, if needed.

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Can Bladder Cancer Impact Sexual Function

It is not uncommon for bladder cancer and its treatments to cause sexual dysfunction in patients.1 The type of effects that a patient experiences depends in large part on the type of treatment for bladder cancer that the patient receives. Patients may experience a decrease in their levels of sexual desire, for both physical and/or emotional reasons. Men may experience issues with getting and maintaining an erection, for example, while women may experience issues with vaginal dryness, irritation or discomfort that can make having sex uncomfortable. However, there are many options for managing and reducing the sexual effects of bladder cancer and many patients are able to regain the ability to have and enjoy sexual activities again.

Things May Never Return To How They Were Pre

I am so used to being so much more active than I am now. Even when I try, I cannot do things that I used to be able to do. It is frustrating. Sometimes it is discouraging. In my head, I feel like I should be back to the way things used to be. I mean, that’s what everyone thinks I should be doing. In reality, I am not and may not ever be.

While I would not ever wish cancer of any type onto anyone, I do wish that the Cancer Muggles would be able to walk a mile in my ultra-supportive, neuropathy-friendly shoes to see what it is like to live the life of a bladder cancer survivor: struggles and all.

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Can Bladder Cancer Cause Sleep Interference And Fatigue

It is not unusual for patients with bladder cancer to experience the symptoms of fatigue and sleep interference.2 Fatigue is a feeling of tiredness and very low energy that generally does not go away after sleeping or resting. Sleep interference includes problems falling asleep, staying asleep, and waking during the night several times and/or for long periods of time. Radiation therapy and chemotherapy, both common treatments for bladder cancer, can cause the symptoms of fatigue and sleep interference. These symptoms can have a significant impact on a patients quality of life, and there are strategies that can be used to help address them.

Bladder Cancer Diagnosis: Imaging

Bladder Cancer, BCG Treatment, and Reactive Arthritis

Intravenous Pyelogram

An intravenous pyelogram is an X-ray test with contrast material to show the uterus, kidneys, and bladder. When testing for bladder cancer, the dye highlights the organs of the urinary tract allowing physicians to spot potential cancer-specific abnormalities.

CT Scans and MRI

CT scans and MRI are often used to identify tumors and trace metastasized cancers as they spread to other organ systems. A CT scan provides a three-dimensional view of the bladder, the rest of the urinary tract, and the pelvis to look for masses and other abnormalities. CT scans are often used in conjunction with Positron emission tomography to highlight cells with high metabolic rates. âHot spotsâ of cells with abnormally high metabolism may indicate the presence of cancer and require further investigation.

Bone Scan

If a tumor is found in the bladder a bone scan may be performed to determine whether the cancer has spread to the bones. A bone scan involves having a small dose of a radioactive substance injected into the veins. A full body scan will show any areas where the cancer may have affected the skeletal system.

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What To Do About Changes When You Urinate

Narrator:What to do about changes when you urinate caused by radiation therapy.

Having problems when you urinate? Listen to solutions from other people undergoing radiation therapy. Also, hear advice from Dr. Ross. Then talk with your own doctor or nurse to learn more.

Miguel:Tip number 1: Drink lots of liquids each day.It’s good for your urine to be clear or a pale yellow color. My doctor says that tells you you’re getting enough liquids. Most people find drinking about 8 cups of liquid a day does the trick. Of course, check to make sure that’s the best amount for you, too.

Cara:Tip number 2: Water is wonderful, but you may want more zip in your sip.I like water, but found it was hard to get enough water each day. I was glad to learn that Jell-O and soups also count as liquids. To add some zip to what I drink, I have water with a little lemon and watered-down juices.

Rodney:Tip number 3: Lose the booze.My doctor told me that wine, liquor, or even beer could really bother my bladder. So now I limit these liquids. Some people may need to stay away from wine, liquor, and beer altogether to avoid irritating their bladder.

My doctor also told me to stay away from caffeine in coffee, colas, or teas. They could make my bladder problems worse. I now choose flavored decaf coffees and tasty herbal teas.

Dr. Ross:Hi, I’m Dr. Ross and you just heard 3 great tips to keep bladder problems under control.

Related Resources
  • January 23, 2020

Living With Bladder Cancer

Cancer is a life-changing experience. And although there’s no surefire way of preventing a recurrence, you can take steps to feel and stay healthy. Eating plenty of fruits, veggies, whole grains, and keeping to modest portions of lean meat is a great start. If you smoke, stop. Limit alcohol to one drink a day for women and up to two drinks a day for men. Daily exercise and regular checkups will also support your health and give you peace of mind.

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Bladder Cancer Symptoms: Bladder Changes

Bladder cancer sometimes causes changes in bladder habits like having to urinate more often or feeling an urgent need to urinate without producing urine. Another symptom of bladder cancer is pain or burning during urination without evidence of a urinary tract infection. These symptoms of bladder problems, like bleeding, are usually caused by conditions other than cancer. In some people, bladder cancer tends to cause no symptoms until it reaches an advanced stage that is difficult to cure.

What Is Gemcitabine

Bladder Cancer Treatments and Their Effects on Women’s Sexuality

Gemcitabine is a chemotherapy drug that is commonly used to treat bladder cancer. It may be given alone or along with cisplatin, another chemotherapy drug. Gemcitabine prevents cancer cells from using DNA properly. Without the use of DNA, cancer cells can no longer grow and live. This stops or prevents bladder cancer from coming back or progressing.6

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Who Can Use Bcg

BCG is a treatment for early-stage bladder cancer that has not yet invaded the muscle of the bladder wall. Called non-muscle invasive bladder cancers or in situ bladder cancers, these account for about half of all bladder cancers.

For 2021, it was estimated that about 83,730 new cases of bladder cancer would be diagnosed in the United States, and about 17,200 American bladder cancer patients would die from the disease.

Side Effects Not Requiring Immediate Medical Attention

Some side effects of bcg may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Burning during first urination after treatment

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, Check with your doctor immediately if you notice the following side effects:

  • Cough

Applies to bcg: intravesical powder for reconstitution, percutaneous powder for injection

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Before You Start Chemotherapy

You need to have blood tests to make sure its safe to start treatment. You have these either a few days before or on the day you start treatment. You have blood tests before each round or cycle of treatment.

Before each treatment you need to stop drinking fluids. This stops the urine from diluting the drug in your bladder and will help you hold the urine more easily. Your hospital will tell you when to stop drinking.

Bladder Cancer Survival Rates

Concurrent Chemo, Immunotherapy Offers Viable Option in ...

Survival rates dont tell a person how long they will live, but they can predict how likely it is that treatment will succeed. People whose cancer hasnt grown past the bladder have a better at living for at least five years with treatment.

These are just guidelines and dont necessarily apply to each individual persons case. If you have questions about your specific prognosis and survival chances, talk to your doctor.

National Cancer Institute Five-Year Survival Rates

  • Average overall 77 percent

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Side Effects Requiring Immediate Medical Attention

Along with its needed effects, bcg may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking bcg:

More common

  • painful urination

Rare

Causes And Risk Factors

Researchers dont know exactly what causes bladder cancer, but they do know what increases the risk of getting it. These risk factors range from family history to certain types of medication.

Source: Valisure

Data published in 2021 on MedRxiv by researchers from the online pharmacy Valisure and Memorial Sloan Kettering Cancer Center showed patients who took Zantac had elevated diagnosis rates of bladder, breast, prostate and thyroid cancer.

Patients should keep in mind that this data suggests a link between ranitidine and increased risk, but it doesnt prove that all people who take ranitidine will get bladder cancer.

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Radiotherapy With A Radiosensitiser

Radiotherapy is given by a machine that beams the radiation at the bladder . Sessions are usually given on a daily basis for five days a week over the course of four to seven weeks. Each session lasts for about 10 to 15 minutes.

A radiosensitiser should also be given alongside radiotherapy for muscle-invasive bladder cancer. This is a medicine which affects the cells of a tumour, to enhance the effect of radiotherapy. It has a much smaller effect on normal tissue.

As well as destroying cancerous cells, radiotherapy can also damage healthy cells, which means it can cause a number of side effects. These include:

  • tightening of the vagina , which can make having sex painful
  • erectile dysfunction
  • tiredness
  • difficulty passing urine

Most of these side effects should pass a few weeks after your treatment finishes, although there’s a chance they’ll be permanent.

Having radiation directed at your pelvis usually means you’ll be infertile for the rest of your life. However, most people treated for bladder cancer are too old to have children, so this isn’t usually a problem.

After having radiotherapy for bladder cancer, you should be offered follow-up appointments every three months for the first two years, then every six months for the next two years, and every year after that. At these appointments, your bladder will be checked using a cystoscopy.

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