What Causes Bladder Wall Thickening
Bladder wall thickening is a common symptom of many diseases. Most commonly it occurs with benign tumors such as cysts, polyps or masses. However, it may also occur in some cancers such as leukemia and lymphomas .
The cause of bladder wall thickening is not known but there are several theories. One theory suggests that it is due to the presence of abnormal cells called microcarcinogens in the body.
These bacteria produce toxins which damage normal tissue. Another theory suggests that it is due to the presence of certain hormones in the blood stream causing inflammation. Other possible reasons include infection, hormonal imbalance, injury and other conditions.
Symptoms of Bladder Wall Thickening:
A lumpy appearance of the skin around your groin area or lower abdomen . This condition may affect both men and women.
The lumpiness usually begins at birth and becomes worse over time.
Pain may or may not occur.
Blood in the urine is very rare. In some cases, there may be no symptoms at all.
If it is a true cyst then it will be separate from the actual bladder wall cysts which are attached to the skin are more likely to be other types of growths such as genital warts.
Weird smells from the urine or skin are rare.
There may be no symptoms at all.
Diagnosis of Bladder Wall Thickening:
A physical examination of the genital region is made. In some cases, a biopsy is done to rule out cancer.
Treatment of Bladder Wall Thickening:
How Is Interstitial Cystitis Diagnosed
Diagnosing interstitial cystitis typically isnt a simple process. There isnt any single medical test that can definitively diagnose IC, or rule it out.
To diagnose IC, your doctor will consider your symptoms and medical history, and perform a physical and neurological exam. Your doctor may also give you a questionnaire about bladder or pelvic pain.
Your doctor may also order or administer other tests to help diagnose IC, or to rule out other health conditions. These tests may include:
Urine tests Simple tests of a urine sample can rule out other conditions by detecting signs of an active infection or blood in your urine.
Ultrasound of bladder This noninvasive test allows doctors to see the shape and structure of your bladder, as well as how well you empty it after urination.
Urodynamic evaluation This test involves filling your bladder with water through a catheter to measure pressure as it fills and empties.
Cystoscopy This procedure involves inserting a specialized viewing instrument into your bladder to look for ulcers caused by IC, or other problems, such as a tumor.
Whats Usually The First Symptom Of Bladder Cancer
Blood in your pee is the most common bladder cancer symptom. That said, simply having blood in your pee isnt a sure sign of bladder cancer. Other conditions cause this issue, too. But you should contact a healthcare provider whenever you spot blood in your pee. Other bladder cancer symptoms include:
- Visible blood in your pee : Healthcare providers can also spot microscopic amounts of blood in pee when they do a urinalysis.
- Pain when you pee : This is a burning or stinging sensation that you may feel when you start to pee or after you pee. Men and DMAB may have pain in their penises before or after peeing.
- Needing to pee a lot: Frequent urination means youre peeing many times during a 24-hour period.
- Having trouble peeing: The flow of your pee may start and stop or the flow may not be as strong as usual.
- Persistent bladder infections: Bladder infections and bladder cancer symptoms have common symptoms. Contact your healthcare provider if you have a bladder infection that doesnt go away after treatment with antibiotics.
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Treatment Of Feline Idiopathic Cystitis
Because the cause of FIC is unknown, theres no medication that directly treats it. The most important aspect of managing FIC is to ease your cats discomfort. Your vet might prescribe pain relievers such as butorphanol or buprenorphine, which are low-dose opioids. Gabapentin is a drug in a different class that may also be used to control pain.
If your cats urethra is blocked, it will require much more extensive treatment. After the initial emergent treatment, some of the medications your vet might prescribe include, but are not limited to acepromazine, prazosin or phenoxybenzamine, which are medications designed to help the urethra relax. Unfortunately, one of the main causes of the blockage is inflammation, and these medications dont address the underlying inflammation.
Given that inflammation is a big part of FIC, you might assume that your vet would advise taking a non-steroidal anti-inflammatory drug like meloxicam. Unfortunately, no studies have demonstrated that NSAIDs help with FIC.
Bladder Cancer Clinical Trials
What about Clinical Trials?
You may hear about clinical trials for your bladder cancer. Clinical trials are research studies that test if a new treatment or procedure is safe and effective.
Through clinical trials, doctors find new ways to improve treatments and the quality of life for people with disease. Trials are available for all stages of cancer. The results of a clinical trial can make a major difference to patients and their families. Please visit our clinical trials research webpage to learn more.
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Symptoms Of Feline Idiopathic Cystitis
Common symptoms of FIC may include:
Straining to urinate
Urinating more often
Urinating smaller amounts more frequently
Blood in the urine
Urinating outside the litter box, especially on cool, smooth surfaces such as tile or hardwood floors
Licking excessively at the genital region
Crying out or meowing while urinating
Vomiting or diarrhea
If your cats urethra has become obstructed , they will produce little to no urine and cry out often. They also will likely exhibit many of the other signs listed above. This is a medical emergency. Please seek veterinary care immediately.
What Are The Treatment Options
Treating a thickened bladder wall means treating the underlying condition that caused the change in the wall.
For example, UTI treatment usually involves a course of antibiotic therapy. To prevent UTIs, practice good hygiene. Wipe front to back to reduce the risk of germs from the rectum reaching the urethra.
Surgery can remove noncancerous tumors that are causing you symptoms. The tumors usually wont recur.
Cancerous growths can sometimes be removed with surgery, too. Additional cancer treatments, such as chemotherapy or radiation, may also be necessary.
Prostate treatment is a somewhat controversial subject. Prostate surgery can sometimes lead to incontinence or erectile dysfunction. If prostate symptoms are minor, your doctor may recommend a watch-and-wait approach to monitor your prostate regularly. Prostate cancer is often a slow-growing cancer. This means aggressive treatment isnt always best.
If excess bladder emptying due to urge incontinence is a problem, your doctor may recommend anticholinergic drugs. These medications relax the detrusor muscle of the bladder.
If urinary retention is occurring due to BOO, your doctor may prescribe medication, such as tamsulosin, to help your urine flow be stronger.
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Urgency Or Difficulty Urinating
A bladder disorder can make it difficult to fully empty your bladder. This can cause frequent urination, feeling like you always have to urinate, or both.
When the bladder wall thickens, the bladder may not be able to hold as much urine as it normally does. This can create those urgent feelings of having to urinate more frequently. BOO can also make it harder to urinate.
What Are The Symptoms Of First Stage Bladder Cancer
Changes in bladder habits or symptoms of irritationHaving to urinate more often than usual.Pain or burning during urination.Feeling as if you need to go right away, even when your bladder isnt full.Having trouble urinating or having a weak urine stream.Having to get up to urinate many times during the night.
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What Is The Treatment For Thickening Of The Bladder Wall
Increased intravesical pressure results from smooth muscle hypertrophy and thus the bladder wall thickens. Alpha-blockerAlpha-blockerThe alpha-1 adrenergic receptor antagonists are a family of agents that bind to and inhibit type 1 alpha-adrenergic receptors and thus inhibit smooth muscle contraction. Their major uses are for hypertension and for symptomatic benign prostatic hypertrophy.https://www.ncbi.nlm.nih.gov books NBK548719Alpha 1 Adrenergic Receptor Antagonists – LiverTox – NCBI therapy is the most preferred medical treatment in patients with LUTS. Bladder wall hypertrophy is caused by a thickening of the detrusor.
What Could A Mass In The Bladder Be
Bladder tumors are abnormal growths that occur in the bladder. If the tumor is benign, its noncancerous and wont spread to other parts of your body. This is in contrast to a tumor thats malignant, which means its cancerous. There are several types of benign tumors that can develop within the bladder.
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There Are Three Ways That Cancer Spreads In The Body
Cancer can spread through tissue, the lymph system, and the blood:
- Tissue. The cancer spreads from where it began by growing into nearby areas.
- Lymph system. The cancer spreads from where it began by getting into the lymph system. The cancer travels through the lymph vessels to other parts of the body.
- Blood. The cancer spreads from where it began by getting into the blood. The cancer travels through the blood vessels to other parts of the body.
Causes Of Bladder Trabeculation
The bladder is a hollow, triangle-shaped organ in your lower abdomen. Other organs and ligaments attached to the bones in your pelvis hold it in place. Your bladder walls typically expand to store urine, then contract to push urine out through your urethra and expel it from your body.
When something blocks the urethra, like a kidney stone, it can slow down or stop urine from getting out. Your bladder walls must work harder as your bladder tries to force out urine. This causes the bladder walls to thicken. That thickening of the bladder walls is called trabeculation.
When your bladder walls get too thick, they lose the ability to expand and contract, making it hard for your body to expel urine.
Bladder trabeculation can be caused by other health conditions, such as blood clots. People who have blood clots may have trouble urinating when the clots harden. This puts pressure on the bladder walls, causing them to thicken. â
Bladder trabeculation in children. Bladder trabeculation in children can be caused by congenital bladder conditions . Certain valves within the urethra can narrow or block the ureter or urethra, causing bladder trabeculation.
Bladder trabeculation can also be caused by other conditions, including:
- Ureter bulging into the bladder
- Fecal impaction â
Bladder trabeculation in men. Benign prostatic hyperplasia in men can block the flow of urine. That can eventually cause trabeculation in the bladder.
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Bladder Cancer Is A Disease In Which Malignant Cells Form In The Tissues Of The Bladder
The bladder is a hollow organ in the lower part of the abdomen. It is shaped like a small balloon and has a muscular wall that allows it to get larger or smaller to store urine made by the kidneys. There are two kidneys, one on each side of the backbone, above the waist. Tiny tubules in the kidneys filter and clean the blood. They take out waste products and make urine. The urine passes from each kidney through a long tube called a ureter into the bladder. The bladder holds the urine until it passes through the urethra and leaves the body.
There are three types of bladder cancer that begin in cells in the lining of the bladder. These cancers are named for the type of cells that become malignant :
- Transitional cell carcinoma: Cancer that begins in cells in the innermost tissue layer of the bladder. These cells are able to stretch when the bladder is full and shrink when it is emptied. Most bladder cancers begin in the transitional cells. Transitional cell carcinoma can be low-grade or high-grade:
- Low-grade transitional cell carcinoma often recurs after treatment, but rarely spreads into the muscle layer of the bladder or to other parts of the body.
- High-grade transitional cell carcinoma often recurs after treatment and often spreads into the muscle layer of the bladder, to other parts of the body, and to lymph nodes. Almost all deaths from bladder cancer are due to high-grade disease.
See the following PDQ summaries for more information:
Duration Of Interstitial Cystitis
Interstitial cystitis isnt considered a curable condition. Instead, treatment for IC is aimed at reducing the burden of symptoms.
Even if you experience an absence of IC symptoms for a period of time which may last weeks, months, or even longer you arent considered cured. Instead, youre considered to be in remission.
While people with interstitial cystitis are typically thought to have the condition for the rest of their lives, that doesnt mean you should resign yourself to pain, discomfort, and disruption. With treatment, most people with IC can significantly improve their condition.
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Causes And Risk Factors Of Interstitial Cystitis
Doctors don’t know the exact cause of interstitial cystitis, but many researchers believe that it is initially triggered by damage to the bladder lining.
In a study published in September 2017 in the journal BMC Chemistry, researchers found that many people with IC produce a protein, called antiproliferative factor, that makes the bladder sensitive to urine.
This protein prevents the growth of bladder cells, so it may prevent the bladder from healing itself when damage occurs.
Many researchers believe that IC may develop for a number of different reasons, such as the following:
Damage to the bladder Surgery or other types of trauma may damage the bladder, contributing to this condition.
Bladder distention The inability to empty your bladder for long periods of time has been associated with interstitial cystitis.
Nerve damage Spinal cord trauma and inflammation of the pelvic nerves have been suspected as causes.
Bacterial infection A bladder infection, or cystitis, may contribute to the onset of IC in some people.
Muscle dysfunction When the pelvic floor muscles arent working right, they may contribute to bladder problems.
Autoimmune disorder Some researchers suspect that the bodys own immune system may attack certain bladder cells in some people with IC.
What Is Interstitial Cystitis Symptoms Causes Diagnosis Treatment And Prevention
Interstitial cystitis is a painful condition in which the bladder wall becomes irritated and inflamed.
Chronic inflammation can cause scarring and thickening of the bladder wall, making the bladder very stiff and unable to hold a normal amount of urine.
Most treatments for IC are aimed at controlling symptoms, and no single treatment works for everyone. But most people eventually achieve significant relief from pain and discomfort.
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Treatment Of Stages Ii And Iii Bladder Cancer
For information about the treatments listed below, see the Treatment Option Overview section.
- Transurethral resection with fulguration.
- A clinical trial of a new treatment.
Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
Some Cancers Are Preventable
Many forms of Cancer come from our environment. The food we eat, the air we breathe, the products we use in our daily life.
You can do this
Dont smoke protect your skin from the sun limit your alcohol consumption maintain a healthy weight do regular physical activity eat healthy food with fruits and vegetables be aware of changes in your body know your familys medical history Have regular check-ups and cancer screenings at the suggested times.
For more information on how you can prevent cancer, please visit the Center for disease Control to learn the basics of prevention.
Check out this list of preventable Cancers from the Prevent Cancer Foundation.
We know that smoking can not only cause cancer but it also blocks your body from fighting off cancer treatments. The poisons found in cigarettes can weaken the bodys immune system, making it harder to kill cancer cells. Today, nearly 9 out of 10 lung cancers are caused by smoking cigarettes and many other cancers can also be caused by smoking. Because of whats in tobacco today, smokers have a greater risk for lung cancer than they did in 1964, even though they may smoke fewer cigarettes. Treatments are getting better for lung cancer, but it still kills more men and women than any other type of cancer. Remember, smoking can cause cancer almost anywhere in your body.
You can reduce your risk of the deadly lung cancer. The soon you stop the better.
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Bladder Wall Thickening In Men And Women
The underlying causes of a thickened bladder wall can differ between men and women.
BOO is more common among men, because its often linked to prostate problems. An enlarged prostate forces the bladder to work harder to empty itself of urine. This in turn causes the bladder wall to thicken. Prostate treatment can help reduce the burden on the bladder.
UTIs are more common among women. Thorough treatment can ease the strain on the bladder and allow thickened bladder walls to return to normal.
How Is Cystitis Diagnosed
A history of hematuria, dysuria, and pollakiuria is strong evidence of some form of cystitis. When any or all of these signs are seen, several tests are appropriate.
The first group of tests includes urinalysis, urine culture, and bladder palpation .
A urinalysis consists of several tests to detect abnormalities in the urine and urine sediment. These are generally adequate to confirm cystitis, but they may not tell us the exact cause.
Urine culture and sensitivity determines if bacteria are present and what antibiotics are likely to be effective in killing them. This is often indicated, because bacteria cause most cases of cystitis in dogs and are usually eliminated easily with the appropriate antibiotic.
Bladder palpation is the first diagnostic test for bladder stones, since stones may be large enough to be felt by your veterinarian.
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