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Can Breast Cancer Metastasis To Bladder

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Some Of The Most Common Signs And Symptoms Of Cancer

Understanding Bladder Cancer | Treating Metastatic Disease

Although every case is different, some general signs and symptoms of cancer include:

Most of the time, these symptoms arent caused by cancer. A benign tumor or another problem may be the culprit. But you shouldnt ignore symptoms that are persistent, severe, or dont go away.

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Local Bladder Cancer Metastasis

When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers. It can take some time for cancer to penetrate all of these layers, but once it has, it can then spread into the surrounding fatty tissues and lymph nodes. Once bladder cancer has reached the lymph nodes, it can travel to distant parts of the body through the lymphatic system. Separately, it can also continue to grow into surrounding areas such as the abdominal wall .

Can High Calcium Levels Be Prevented

There are things you can do to help prevent high calcium levels. The following tips may help keep hypercalcemia from getting worse:

  • Drink fluids regularly.

  • Talk with your doctor about controlling your nausea and vomiting.

  • Walk and be active, which can help stop bone from breaking down.

  • Check with your doctor before taking any medication, including over-the-counter supplements. Some may make high calcium levels worse.

Also Check: Kegel Exercises For Bladder Control

Clues That Your Cancer Has Spread

Symptoms may be different or more intense if your cancer has metastasized to other parts of your body.

Here are some common symptoms of cancer that has spread:

  • Bone metastasis Cancer that has spread to the bones may cause joint pain or fractures.
  • Liver metastasis If your disease has invaded your liver, you might experience jaundice and swelling in your abdomen.
  • Brain metastasis When cancer metastasizes to the brain, symptoms may include headaches, speech difficulties, blurred vision, or dizziness.
  • Lung metastasis Cancer that has spread to the lungs may trigger shortness of breath or a persistent cough.

Testing Pee For Pancreatic Cancer

Breast cancer metastasis to the bladder: a literature review

At the moment theres no easy way to diagnose pancreatic cancer at an early stage. A diagnosis usually involves a series of scans and invasive biopsies that are normally done once a person has developed symptoms. But by the time they show signs of illness, the disease is usually too advanced to be treated successfully.

A group of our scientists in London want to change this.

We started like everybody else, says Professor Tatjana Crnogorac-Jurcevic from Queen Mary, University of London, and began looking in the blood for pancreatic cancer. Her team soon realised blood was teeming with molecules released from all kinds of other cells.

Urine is a lot less crowded. Crnogorac-Jurcevic says around 40% of material found in urine is from outside the kidneys and urinary tract. The blood plasma is filtered through the kidneys, so you can detect lots of things in it.

After 15 years of hard work, Crnogorac-Jurcevic and her team have found 3 key proteins linked to pancreatic cancer that successfully flag up its presence in pee.

She says that people often use the analogy for early detection as looking for a needle in a haystack. Weve already gone through the haystack and found our needles, so now its really a matter of evaluating our test on large samples of patients.

Excitingly, the clinical trial testing this pancreatic cancer-detecting tool is about to start recruiting patients.


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Metastatic Cancer: What Happens When Cancer Spreads

If youve recently received a cancer diagnosis, you may have heard the word metastasis or been asked by someone if your cancer has metastasized. But, what is metastasis? What does it mean for your cancer treatment? And is it curable?

We got details on metastasis from Jeffrey Gershenwald, M.D., a surgical oncologist who specializes in the care of patients with melanoma and has contributed to the worlds leading guides on melanoma staging.

What is cancer metastasis?

Cancer occurs when an abnormal cell inside the human body duplicates. Sometimes these cells form a mass called a tumor. When those cells spread from the original site they started in and spread to other places in the body, theyre called metastases. In other words, when cancer has metastasized, we mean it has spread.

We classify cancer by where it starts, no matter where it spreads to. Breast cancer is cancer that started in the breast, and bladder cancer is cancer that started in the bladder. When bladder cancer spreads to a region like the liver, for example, the patient does not have liver cancer and bladder cancer. We consider the bladder cancer to be whats called the primary cancer, and the liver to be the site of the metastases.

What stage is metastatic cancer?

It differs depending on the cancer type, but in most cases, cancer that has spread to distant organs is stage IV cancer. If cancer has spread to nearby lymph nodes or other close tissues, its generally stage III.

Is metastatic cancer curable?

How Does Cancer Cause Signs And Symptoms

When cancer grows, it can push on nearby organs, nerves, and blood vessels, which can cause signs and symptoms. Even the smallest tumors can cause symptoms in certain organs, such as the brain.

If your cancer spreads, or metastasizes, you may notice signs or symptoms in different parts of your body.

Another reason you may experience symptoms is that cancer cells use up a lot of your bodys energy supply. They also cause changes in how your immune system works.

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Bladder Cancer Risk Factors

Each year, more than 80,000 Americans are diagnosed with bladder cancer. Anyone can get bladder cancer, but factors such as age, race and gender may increase the risk of the disease. Knowing behavior-related risk factors for bladder cancer may help you take preventive measures to reduce your chances of developing the disease or may help you and your doctor detect signs of bladder cancer earlier.

What Will Happen After Treatment

UROWebinar: New insights in treatment of bladder cancer From localized to metastatic diseases

You’ll be glad when treatment is over. But its hard not to worry about cancer coming back. Even when cancer never comes back, people still worry about this. For years after treatment ends, you will see your cancer doctor. Be sure to go to all of your follow-up visits. People who have had bladder cancer are at high risk of having a second bladder cancer.

If you have no signs of cancer, most experts advise seeing with your doctor every 3 to 6 months. These visits might include urine tests, blood work, and other tests. If you still have your bladder, you will need regular exams of your bladder, too. The time between doctor visits may be longer after a few years if no new cancers are seen.

Having cancer and dealing with treatment can be hard, but it can also be a time to look at your life in new ways. You might be thinking about how to improve your health. Call us or talk to your doctor to find out what you can do to feel better.

You cant change the fact that you have cancer. What you can change is how you live the rest of your life making healthy choices and feeling as well as you can.

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What Is Bladder Cancer

Cancer can start any place in the body. Cancer that starts in the bladder is called bladder cancer. It starts when cells in the bladder grow out of control and crowd out normal cells. This makes it hard for the body to work the way it should.

Cancer cells can spread to other parts of the body. For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, its called metastasis.

Cancer is always named for the place where it starts. So when bladder cancer spreads to the bone , it’s still called bladder cancer. Its not called bone cancer unless it starts in the bone.

Breast Cancer Metastasis To Urinary Bladder Related Hematuria And Concomitant Venous Thromboembolismcase Report Of A Challenging Clinical Scenario

Chek Hao Foo1, Wai Loon Yam2, Chien Sheng Tan3, Joon Jae Park2

1 Lee Kong Chian School of Medicine ,

Correspondence to:

Keywords: Breast cancer urinary bladder venous thromboembolism inferior vena cava filter case report

Received: 02 August 2020 Accepted: 16 October 2020 Published: 30 December 2020.

doi: 10.21037/abs-20-90

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Surgery For Bladder Cancer

Surgery is done for most bladder cancers. The type you have depends on the stage of the cancer.

Removing the tumor from the inside bladder is the most common surgery for early bladder cancer. This can be done during a cystoscopy. A a cystoscope with a looped wire on the end is used to remove the tumor.

When the cancer is more invasive, the cancer is removed along with part of the bladder or the entire bladder.

If only part of the bladder is removed, you’ll still be able to hold and release urine as normal, though in smaller amounts. If the entire bladder is removed, you’ll need another way to store and pass urine. Your doctor can explain the options for this.

Side effects of surgery

Any type of surgery can have some risks and side effects. For instance, removing the bladder not only changes how your body passes urine, but it can also cause sexual side effects. If you have these or any other problems, let your doctors know. There are ways to help deal with many side effects.

Can Breast Cancer Cause Bladder Problems

Bladder metastasis from primary breast cancer: a case report

The problem is that breast cancer treatments tend to reduce essential sex hormones in a womans body, namely estrogen and progesterone. When these hormones drop, they can lead to urinary problems such as urinary tract infections, bladder infections, or incontinence issues.

What cancers are associated with bladder cancer?

In the 342 cases with only two primary cancers , the two most common cancers associated with bladder cancer were stomach cancer and prostate cancer in males and cancer of the cervix and stomach in females.

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What Is The Most Common Bladder Cancer Or Breast Cancer

We carefully reviewed and systematically reported data regarding epidemiology, pattern of spread, signs and symptoms, pathology and hormonal status, diagnostic workup, management, and outcomes. Urinary bladder metastases from breast cancers are more common in invasive lobular carcinoma.

Can a person with bladder cancer get another cancer?

This is called a second cancer. Being treated for bladder cancer does not mean you cannot have another cancer. Bladder cancer survivors can get any type of second cancer, but they are at an increased risk of these cancers compared to the general population: A second bladder cancer

What Is Metastatic Cancer

Metastatic cancer refers to cancer that has spread beyond the point of origin to other, distant areas of the body. To fully understand metastatic cancer, well first define metastasis:

Metastasis is a word used to describe the spread of cancer. Unlike normal cells, cancer cells have the ability to grow outside of the place in your body where they originated. When this happens, its called metastatic cancer, advanced cancer or Stage IV cancer. Nearly all types of cancer have the potential to metastasize, but whether they do depends on a number of factors. Metastatic tumors can occur in three ways:

  • They can grow directly into the tissue surrounding the tumor.
  • Cancer cells can travel through your bloodstream to distant locations in your body.
  • Cancer cells can travel through your lymph system to nearby or distant lymph nodes.
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    Asymptomatic Bladder Metastasis From Breast Cancer

    Luigi Cormio

    1Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy

    2Department of Pathology, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, Italy


    Introduction. Breast cancer is the most common nondermatologic cancer in women. Common metastatic sites include lymph nodes, lung, liver, and bone. Metastases to the bladder are extremely rare, with all reported cases presenting with urinary symptoms. Case Report. Herein, we report the first case of completely asymptomatic bladder metastasis from breast cancer, occasionally revealed, 98 months after the initial diagnosis of lobular breast carcinoma, by a follow-up computed tomography scanning showing thickening of left bladder wall and grade II left hydronephrosis. A positive staining for estrogen and progesterone receptors was confirmed by immunohistochemistry. Discussion. The reported case confirms that bladder metastases from breast cancer tend to occur late after the diagnosis of the primary tumor and, for the first time, points out they can be asymptomatic. Such data support the need for careful follow-up and early intervention whenever such clinical situation is suspected.

    1. Introduction

    2. Case Report

    Abdominal computed tomography scanning showing thickening of the left bladder wall with grade II left hydronephrosis .

    3. Discussion

    4. Conclusions


    Cancers Likely To Metastasize

    Treatment Options for Advanced and Metastatic Bladder Cancer

    You may be surprised to learn that lung metastases are quite common. While almost any cancer can spread to the lungs, some are more likely than others to do so. With that, the most common types of cancer that metastasize to the lungs include:

    • Thyroid cancer
    • Uterine cancer

    Pulmonary metastases occur also very often in sarcoma, a relatively rare type of cancer. As many as 20% of soft tissue sarcomas and up to 40% of bone sarcomas develop lung metastases.

    Occasionally, healthcare providers are unable to determine the primary site of cancer. In this case, they refer to the cancer as a cancer of unknown origin with metastasis to the lungs.

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    Questions To Ask The Doctor

    • What treatment do you think is best for me?
    • Whats the goal of this treatment? Do you think it could cure the cancer?
    • Will treatment include surgery? If so, who will do the surgery?
    • What will the surgery be like?
    • How will I pee after surgery?
    • Will I have other types of treatment, too?
    • Whats the goal of these treatments?
    • What side effects could I have from these treatments?
    • Is there a clinical trial that might be right for me?
    • What about treatments like special vitamins or diets that friends tell me about? How will I know if they are safe?
    • What should I do to be ready for treatment?
    • Is there anything I can do to help the treatment work better?
    • Whats the next step?

    Where Can I Find A Support Group

    To find a local group, talk to your healthcare provider. Local and Zoom meeting lists are also available through organizations such as CancerCare.

    Joining a support group of people dealing with advanced cancer may help provide camaraderie and knowledge. You can connect with people who understand what you’re going through.

    Treating cancer means looking after your whole self. This includes keeping an active lifestyle, eating healthy, practicing mindfulness, and socializing with family and friends to improve your mood and overall health. If you smoke cigarettes or use nicotine products, this is a good time to try to quit or cut down.

    It’s also important to look after your mental health. Meeting with a therapist can help you navigate intense emotions and provide you with tools to feel more in control of your daily life.

    Palliative care may also be beneficial. Your palliative care provider can help you learn about pain management options. Palliative care providers can also assist with finding mental health services, such as counseling.

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    What Kind Of Treatment Will I Need

    There are many ways to treat bladder cancer. You might want to get a second opinion about the best treatment plan for you.

    Bladder cancer is most often treated with:

    • Surgery
    • Chemo
    • Immunotherapy

    Sometimes more than one type is used. The treatment plan thats best for you depends on:

    • The stage and grade of the cancer
    • Whether the cancer has spread into the bladder wall
    • The chance that a type of treatment will cure the cancer or help in some way
    • Other health problems you have
    • Your feelings about the treatment and the side effects that come with it

    Complications Related To Lung Metastases

    Asymptomatic Bladder Metastasis from Breast Cancer

    The lungs are the second most common site to which breast cancer spreads, with lung metastases occurring in roughly a third of people with metastatic breast cancer.

    Sometimes this doesnt cause symptoms, and the lung metastases might only be found on an imaging test. The most common symptom is shortness of breath.

    Local treatments, such as radiation or surgery, are sometimes used for the treatment of one or more lung metastases, and this may improve life expectancy.

    Also Check: Bladder And Prostate Cancer Symptoms

    How Is Metastatic Bladder Cancer Treated

    The way that metastatic bladder cancer is treated depends primarily on where the cancer has spread and the type of cells that make up the primary tumor. Its important to remember that when bladder cancer spreads, the secondary tumors are still considered to be bladder cancer not lung cancer, liver cancer or any other type of malignancy. Potential treatment options may include chemotherapy, radiation therapy and clinical trials.

    At Moffitt Cancer Center, weve treated many patients with metastatic bladder cancer, creating tailored treatment plans for every single one. To help ease the burdens of treatment, we also offer comprehensive supportive care services for patients and their caregivers.

    If youd like to request an appointment with one of our experienced oncologists, you can do so by calling or submitting a new patient registration form. Referrals are welcome, but never required.

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    What About Other Treatments That I Hear About

    When you have cancer you might hear about other ways to treat cancer or treat your symptoms. These may not always be standard medical treatments. These treatments can be vitamins, herbs, special diets, and other things. You may be curious about these treatments.

    Some of these are known to help, but many have not been tested. Some have been shown not to be helpful. A few have even been found to be harmful. Talk to your doctor about anything you’re thinking about using, whether its a vitamin, a diet, or anything else.

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