Monday, January 30, 2023

Can Overactive Bladder Cause Kidney Damage

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What Are The Symptoms Of An Overactive Bladder

Overactive Bladder, Causes, Signs and Symptoms, Diagnosis and Treatment.

Overactive bladder symptoms can include:

  • Sudden and overwhelming urge to urinate This symptom can come on very quickly and without any warning.
  • Urge incontinence This happens when you suddenly leak urine after feeling an urgent and immediate need to go to the toilet. Theres also a feeling of not being able to reach the toilet fast enough.
  • Frequency This is the need to urinate more often than usual sometimes more than eight times within a 24 hour period. Often the need to urinate is ever-present whether fluid intake is limited or not.
  • Nocturia This occurs when an overactive bladder wakes you to use the toilet several times during the night to the point where your sleep cycle is disrupted.

Key Points About Neurogenic Bladder

  • In neurogenic bladder, the nerves that carry messages back-and-forth between the bladder and the spinal cord and brain dont work the way they should.
  • Damage or changes in the nervous system and infection can cause neurogenic bladder.
  • Treatment is aimed at preventing kidney damage. It may include medicine, urinary catheters, antibiotics to reduce the chance of infection, and, in severe cases, surgery.
  • Some complications of include urine leakage, inability to pass urine, kidney damage, and kidney or urinary tract infections.

What Questions Should I Ask A Healthcare Provider

  • How do you know that I have an overactive bladder?
  • Whats the cause of my overactive bladder?
  • Whats a normal number of times to pee each day?
  • How much should I drink each day?
  • What fluids should I drink?
  • What fluids should I avoid drinking?
  • What foods should I eat?
  • What foods should I avoid eating?
  • What treatments do you recommend?
  • Are there any side effects to your recommended treatment?
  • What medications do you recommend?
  • Are there any side effects to your recommended medications?
  • Are there any other lifestyle changes I can make?
  • Can you recommend a support group for people with overactive bladder?

A note from Cleveland Clinic

Overactive bladder is a common condition that causes changes in your bathroom habits, which can be embarrassing. Many people struggle to talk to a healthcare provider about their symptoms. However, providers can help answer any of your questions without judgment. They can determine the cause of your overactive bladder and work with you to develop the best treatment plan. If you have symptoms of overactive bladder, talk to a healthcare provider so you can regain control of your bathroom habits and improve your quality of life.

Also Check: How To Fix A Fallen Bladder

The Difference Between Overactive Bladder And Uti

Two-thirds of women experience urinary tract discomfort. If youre one of them, you might be wondering if a urinary tract infection or an overactive bladder is the cause. Both urinary tract infection UTI and overactive bladder are characterized by a Read More

Two-thirds of women experience urinary tract discomfort. If youre one of them, you might be wondering if a urinary tract infection or an overactive bladder is the cause.

Both urinary tract infection UTI and overactive bladder are characterized by a strong, frequent urge to urinate. That can make it difficult to know if your symptoms are the result of an overactive bladder or UTI. In fact, research finds that many women with overactive bladder are often misdiagnosed with UTI, resulting in improper treatment and overuse of unnecessary antibiotics.

Despite their overlapping symptoms, UTI and overactive bladder are completely different conditions. Overactive bladder, as its name hints, happens when the bladder muscles contract excessively. A UTI, by comparison, is most often a bacterial infection of the bladder, although it can occasionally infect the kidneys.

How can you tell the difference between overactive bladder and UTI? Here are the symptoms, causes and treatments to know about.

Treatment Of Irritable Bladder

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There is no blanket treatment for irritable bladder syndrome. It largely depends on the underlying cause. The following are standards treatments applied today.

  • Antibiotics: Usually prescribed for irritable bladder due to infection
  • Bladder training: A technique that teaches the bladder to gain control and improve voiding times. It begins with the patient literally scheduling a bathroom visit even if he or she does not feel like there is a need to go at that specific time. The interval between bathroom visits is gradually increased towards a goal of about four hours. This idea is that the body adapts to these times and incontinence is eliminated.
  • Antispasmodics: Drugs that relax the bladder muscles and can help prevent uncontrolled bladder contractions.

It is important to know that pads and diapers are widely marketed today, but many doctors dont recommend them for long-term use. They like to see their patients try to address the problem head-on with some of the approaches listed above or even with home remedies.

Also Check: How Does Overactive Bladder Medication Work

Read Also: Non Invasive Muscle Bladder Cancer

Is There A Connection Between Uti And Incontinence

Urinary incontinence can affect anybody at any age, but it is more common when we get older and in connection with other medical conditions. Therefore, it is not unusual for people with urinary incontinence to have additional problems that contribute to a higher risk of UTI. Some examples include not being able to completely empty the bladder, reduced immune defence functions, and chronic illnesses. Bowel incontinence is another factor that increases the risk of infection.

Read Also: How Long Can You Live With Untreated Bladder Cancer

Overactive Bladder At Night

If you find that you wake up to urinate more than one time per night, you may have a condition called nocturia, or overactive bladder at night. Nocturia isnt the same as overactive bladder. In fact, some people who experience no OAB symptoms during the day can still have nocturia.

Nocturia is more common in people over age 60, but one in three adults over 30 need two or more trips to the bathroom each night. Most adults can sleep six to eight hours without waking up. Others may only need to wake up once.

If you require more bathrooms breaks during your slumber, you may be experiencing overactive bladder at night.

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How Is Bladder Pain Syndrome Treated

There is no cure for bladder pain syndrome. But your doctor will try different treatments to figure out how to improve your symptoms.

The first treatment many people try includes steps you can take at home. Sometimes, by changing what you eat, you can make your symptoms go away. But even when symptoms do go away, they may return days or years later.

If your symptoms do not get better, other treatments your doctor may suggest include:10

Recommended Reading: What Should I Do If I Have A Bladder Infection

When You’re Drinking Too Much Water

Urinary incontinence – causes, symptoms, diagnosis, treatment, pathology

In most people, with normal kidney function, drinking too much water can irritate your bladder increasing the risk of urine leakage. As fluid intake increases, the amount of urine made will increase along with it. Because the bladder can only hold so much fluid volume, increasing water intake will increase the frequency of urination, and may make people with an overactive bladder more likely to leak. If you have overactive bladder , more fluid intake typically equals more trips to the bathroom. If those fluids are carbonated, they may aggravate your symptoms even more.

Keep in mind that too little fluid intake also isnât ideal. If you drink too little, your urine may become concentrated and acidic, heightening bowel irritation. It is important to work with your doctor to find the amount of water right for you.

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What Is The Main Cause Of Overactive Bladder

Conditions or injuries that affect your detrusor muscle cause overactive bladder. Your detrusor muscle is a collection of smooth muscle fibers in the wall of your bladder. These conditions may include:

  • Abdominal trauma. Pregnancy and childbirth can stretch and weaken your pelvic muscles. Your pelvic muscles are the muscles and tissues that support the organs in your lower abdomen. Your bladder may sag out of its normal position if your pelvic muscles weaken.
  • Nerve damage. Sometimes your body sends signals to your brain and bladder to pee at the wrong time. Certain diseases and trauma can cause nerve damage, including pelvic or back surgery, herniated discs, radiation therapy, Parkinsons disease, multiple sclerosis or a stroke.
  • Medications, alcohol and caffeine. All of these can dull your nerves, which affect signals to your brain and cause your bladder to overflow. Diuretics and caffeine may cause your bladder to fill rapidly and potentially leak.
  • Infection. An infection, such as a urinary tract infection , can irritate your bladder nerves and cause your bladder to squeeze without warning.
  • Extra weight. Having overweight can put extra pressure on your bladder, which can cause urge incontinence.
  • Estrogen deficiency after menopause. Hormonal changes may cause urge incontinence. Vaginal-only estrogen therapy can help.

Searching For The Evidence: Literature Search Strategies For Identification Of Relevant Studies To Answer The Key Questions

We will utilize bibliographic database searching to identify previous systematic reviews, randomized controlled trials, and observational studies published from 1946 to the present for studies enrolling adults based on a diagnosis of CUR. Relevant bibliographic databases for this topic include MEDLINE® and the Cochrane Central Register of Controlled Trials . Our preliminary search strategy appears in Appendix A. This search strategy searches on only one concept, CUR, and employs relevant Medical Subject Headings and natural language terms to find studies on the topic. The concept search is supplemented with filters designed to select experimental designs. Bibliographic database searches will be supplemented with backward citation searches of highly relevant systematic reviews. We will update searches while the draft report is under public/peer review.

We will conduct additional grey literature searching to identify relevant completed and ongoing studies. Relevant grey literature resources include trial registries and U.S. Food and Drug Administration databases. We will search ClinicalTrials.gov and the International Controlled Trials Registry Platform . We will also review Scientific Information Packets sent by manufacturers of relevant interventions. Grey literature search results will be used to identify studies, outcomes, and analyses not reported in the published literature to assess publication and reporting bias.

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Causes Of Total Incontinence

Total incontinence is when your bladder cannot store any urine at all. It can mean you either pass large amounts of urine constantly, or you pass urine occasionally with frequent leaking in between.

Total incontinence can be caused by:

  • a problem with your bladder from birth
  • injury to your spinal cord this can disrupt the nerve signals between your brain and your bladder

First Some Fast Facts

Is it Overactive Bladder or Stress Urinary Incontinence?

There are two types of strokes, ischemic stroke, and hemorrhagic stroke.

The ischemic stroke is the more common one, and it occurs when a blood clot blocks a blood vessel in the brain, causing brain cells to quickly die from the lack of blood circulation and oxygen, which in turn causes the body to lose some neurological functions. The ischemic stroke can also occur when plaque builds up inside an artery, causing it to narrow and eventually become blocked.

If you have suffered a mini ischemic stroke , you are at risk of suffering a more serious one.

Hemorrhagic stroke is the second type, and it happens when the blood vessel bursts or leaks.

In the United States, stroke is the fifth leading cause of adult death and disability, and nearly 800,000 people experience strokes each year.

These conditions can make you more at risk of stroke: diabetes, heart disease, obesity, and high cholesterol level.

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Study Design And Subjects

We performed an observational, cross-sectional study on 83 clinically stable CKD outpatients, enrolled from January 2016 to December 2016, at the University Hospital âPoliclinico Umberto Iâ of Rome, Sapienza University of Rome, Italy. The study included patients with CKD on conservative therapy , Stage 1/5, and/or proteinuria, and/or hypertension and/or recurrent UTIs. Statins, antihypertensive, antiplatelet therapies and/or therapies with calcium, calcitriol and phosphate binders were continued in all patients included in the study. We recorded the anamnesis and excluded patients with urological or malformative pathologies and secondary nephropathies already known, severe infectious pathologies or malignancy in progress, patients with severe heart disease or acute cardiac failure, degenerative neurological or psychiatric diseases, which did not allow the tests to be carried out properly, and acute coronary syndrome or stroke, within 3months before the study. We did not enrol patients who refused to give consent or patients with missing data. The patients carried out two questionnaires, the International Prostate Symptom Score and Incontinence Questionnaire-Short Form , and they also underwent uroflowmetry. eGFR was calculated with the abbreviated Modification of Diet in Renal Disease formula, expressed in mL/min/1.73m2 as defined by Levey et al. .

Causes Of Overactive Bladder

If youve recently been diagnosed with OAB or think you may have it, here are some possible causes of your condition, which are not age-related.

  • Diabetic neuropathy

In these situations, the nerve signals that tell us when to go get disrupted. If trauma occurred during a surgery, OAB can be only temporary. But depending on the results of the surgery, it can be long-lasting as well.Medications

Although medications are prescribed to help a condition, they can lead to other issues such as OAB. Water pills, for example, are often prescribed for blood pressure to make sodium leave the system. In turn, they can cause a higher frequency of urination. Furthermore, pills containing caffeine also work as a diuretic and can make you visit the washroom more often, too.

Often, certain medications require you to drink more fluid, once again causing the symptoms of OAB. So if youre finding your treatment is causing you to urinate more, speak with your doctor about possible alternatives.

Medical conditions

In the case of UTIs, bacteria causes an infection, making the walls of the bladder more active. A UTI can easily be treated with antibiotics, so the OAB symptoms will subside soon after.

Diet

Your diet is an important aspect in controlling your OAB. If youve been diagnosed with overactive bladder, you should steer clear of acidic foods like tomatoes and oranges, curb your intake of caffeine and alcohol, stay hydrated, and get enough fiber.

Read Also: Ways To Strengthen Your Bladder

How Can I Tell If I Have Urinary Incontinence

If you are having urine leakage, you should seek medical care to find out the cause. The doctor will ask you about your medical history and order laboratory tests. The doctor will also examine you. Sometimes, special tests may be done. In one of these, the bladder is filled with fluid. You will then be asked to repeat the action that usually causes you to have urine leakage, such as coughing or straining. X-rays and other measurements are then done to help the doctor find out why you are having the urine leakage.

What Should You Do If You Are Having Symptoms

Postrenal acute kidney injury (acute renal failure) – causes, symptoms, & pathology

It is important to talk with your health care provider and find out what is causing your symptoms. The symptoms of neurogenic bladder may seem like the symptoms of other illnesses and medical problems. Your health care provider can help rule out other issues.

Sometimes neurogenic bladder symptoms can lead to more serious bladder problems. But there are a number of treatments available. You and your health care provider can decide which treatment is best for you.

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What Is The Difference Between Lower And Upper Utis

The most common type of UTI occurs in the lower urinary tract, infecting the urethra and bladder. Highly virulent strains can, if left untreated, spread up to the ureters and kidneys in the upper urinary tract.

Upper UTI symptoms are considerably worse, and may include back pain, nausea and fever. Such a kidney infection is serious and can potentially damage the kidneys or even cause kidney failure. If left untreated it can also lead to urosepsis, which is when the infection enters the bloodstream. This condition requires intensive care.

Which Medications Can Cause Oab

Some medications help with an overactive bladder and are used to treat the condition. But in other instances, your medications may be the culprit leading to urinary urgency.There are several classes of medications that may lead to OAB, including the following:

1. Diuretics

Diuretics are a type of medication that helps stimulate the kidneys to get rid of water and salt from the body in the form of urine. It is prescribed for people who may retain fluid. One of the most common drugs used is Lasix. Because it stimulates the body to make more urine, it often causes OAB.

Is Botox for overactive bladder an effective treatment option? People report an improvement in symptoms, but there are some risks to consider.

2. Blood Pressure Medications

Alpha-blockers are a type of medication used to reduce blood pressure. They work by dilating the blood vessels in the body, which can increase urinary urgency. Examples of alpha-blockers include prazosin and doxazosin mesylate.

3. Antidepressants

Different antidepressant medications may prevent the bladder from emptying completely. This may cause an increased urgency to use the bathroom. Some antidepressants also decrease a persons awareness that they need to urinate, which can lead to urinary incontinence.

4. Narcotic Pain Medications

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What Causes Bedwetting In Children

Nighttime wetting is often related to slow physical development, a family history of bedwetting, or making too much urine at night. In many cases, there is more than one cause. Children almost never wet the bed on purposeand most children who wet the bed are physically and emotionally normal.

Sometimes a health condition can lead to bedwetting, such as diabetes or constipation.

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